Don't panic. The drive is encrypted — without your PIN or both security keys, no one can read what's on it. Email team@leftinpeace.com and we'll walk you through replacing it and changing any passwords you'd stored.
If you downloaded a backup copy (More options... → Download a Backup Copy) with version 1.9.6 or later, you can put it onto a new, empty drive: the new drive's first screen has a link, "Replacing a lost or damaged drive? Put a backup file onto this drive." The new drive keeps the same PIN and the same word cards. That backup file is protected the same way as the drive — your PIN or both cards — so keep it somewhere just as safe, not emailed around or left on a shared computer.
You can also keep a spare: copy everything on your Left In Peace drive onto a second USB drive (More options... → Copy to a New Drive shows how). The spare opens with the same PIN and the same word cards. Keep it somewhere as safe as the original, and copy again now and then so it stays up to date.